Acute Crohn's disease – Example
This 16-year-old white female has had abdominal pain for several weeks. Stools have always been normal. A careful history reveals that she had had similar symptoms about one year ago.
The video shows passages from the transverse and sigmoid colon. There are numerous aphthous changes only a few millimeters in diameter. The lesions are covered with a yellowish-white material and some are surrounded by areas of erythema. These changes lie in an area with completely normal vascular structure. In some areas, these lesions are so discrete that they may be overlooked. These changes are typical for acute Crohn’s disease.
The aphthous changes are typical but not confirmatory for Crohn’s disease. Biopsies should be taken not only from lesions but also from areas of macroscopically normal mucosa, because these areas especially may contain granulomas that are histologically typical for the disease.