Adenomatosis coli 2
The mother of this 16-year-old white male adolescent was diagnosed with colon carcinoma at age 35 years. Her endoscopic and surgical findings were consistent with adenomatosis coli with colon carcinoma (T3) in the ascending colon and numerous adenomas of varying stages of dysplasia. Because of these findings, a colonoscopic examination of her only child was recommended. The family history was significant for a maternal grandfather who had reportedly died at age 46 years from “liver cancer”. The exact diagnosis, however, could not be discovered.
The videoclip shows findings in the sigmoid colon with numerous small polyps, which are of the color of the mucosa and up to 1 cm in diameter. Polyps were excised from several sites in the colon. Histological examination revealed exclusively small tubular adenomas without evidence of dysplasia.
This constellation is consistent with familial adenomatosis coli. The papilla was endoscopically normal. Polypoid lesions in the small bowel were not detected. Findings were discussed with the boy and both parents. The patient was advised to undergo proctocolectomy and examination of all family members was recommended.